Association of fluoride poisoning and Iodine deficiency disorders in children

  • A study conducted in children living in endemic areas of Fluorosis in New Delhi and having Dental Fluorosis has revealed abnormalities in FT3, FT4 and TSH.
  • It was also evident from children chosen as control subjects, consuming safe water, and without Dental Fluorosis, revealed high fluoride levels in blood and urine (presumably consumed through food) also revealed abnormalities in FT3, FT4 and TSH.
  • The primary cause of IDD may not always be iodine deficiency, but it might be induced by fluoride poisoning.
  • Testing of drinking water, body fluids for fluoride content along with FT3, FT4 and TSH, even in children without Dental Fluorosis is desirable for recognizing thyroid derangements.
  • Prevention and control of Fluorosis and IDD require an integrated approach for diagnosis and patient management, contrary to the prevailing practises.